Mar. 20, 2013—A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.
Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.
Feb. 4, 2013—The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.
Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.
Nov. 15, 2012—Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention.
Oct. 23, 2012—The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.
Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.
Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.
Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.
Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.
Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.