cancer biology
In search of new cancer targets
Sep. 9, 2016—Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers.
Proliferative capacity of neuroblastoma
Aug. 31, 2016—The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.
New breast cancer driver
Aug. 26, 2016—Vanderbilt investigators have demonstrated that a certain protein complex drives tumor progression in aggressive breast cancers.
Lovly tapped to brief Congress on cancer research
Jun. 22, 2016—Christine Lovly, M.D., Ph.D., assistant professor of Medicine and Cancer Biology, has been selected to testify before members of Congress about the importance of cancer research, including early training programs for individuals interested in science.
Pulmonary fibrosis culprits
Jun. 6, 2016—New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.
Thompson’s Discovery Lecture
May. 12, 2016—Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, spoke about his lab’s research linking metabolism to stem cell maintenance during his recent Flexner Discovery Lecture.
Current cancer drug discovery method flawed: VUMC study
May. 5, 2016—The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers reported May 2 in Nature Methods.
Drug combos for glioblastoma
May. 3, 2016—Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.
An Argonaute’s voyage to cancer
Apr. 28, 2016—A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”
Cancer expert Thompson to deliver May 5 Flexner Discovery Lecture
Apr. 28, 2016—Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, will deliver the next Flexner Discovery Lecture on May 5.
New role identified for p73 gene
Apr. 1, 2016—The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.
Melanoma response to immune therapy
Mar. 3, 2016—Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.