Breast Cancer Research Foundation
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Research Snapshot: DNA replication discovery opens pathways to understanding and treating cancer, aging and degenerative disease
An international collaboration led by biochemist David Cortez reached revelatory conclusions in exploration of how cells tolerate DNA damage and genome instability. Est. reading time: 2 mins. Read MoreMay 2, 2023
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Researchers discover that protein switches functions to regulate DNA replication
Vanderbilt biochemists have discovered that the protein RADX has different biological effects at sites of DNA synthesis, depending on the cellular conditions — even though it works the same way in both stressed and unstressed cells. Read MoreJul 22, 2021
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A potential new targeted therapy for metastatic melanoma
While 60 percent of people with metastatic melanoma, an aggressive type of skin cancer, have multiple treatment options available to them, roughly 40 percent either do not respond to treatment, or relapse. Read MoreAug 19, 2020
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A catalog of DNA replication proteins
Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA. Read MoreOct 3, 2019