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BRAF Archives

PET imaging to predict tumor response

Jun. 14, 2017—A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

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Health and Medicine Reporter Research


Investigators find clues to melanoma treatment resistance

Oct. 29, 2015—Nearly half of all patients with malignant melanoma, the most deadly form of skin cancer, have a mutation in the BRAF gene found in their tumors. Mutations in the BRAF gene turn on a cancer growth switch known as the MAP kinase pathway.

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Health and Medicine Healthcare Solutions Reporter Research


Combined drug therapy may delay melanoma progression

Oct. 25, 2012—Combination therapy with two drugs delayed the development of treatment resistance in patients with metastatic melanoma that expresses a specific mutation in the BRAF gene.

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Reporter


Study finds mutation in melanoma sensitive to drug

Jul. 26, 2012—An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to a specific drug therapy, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation.

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Health and Medicine Reporter Research


New drug mutes more melanomas

Apr. 26, 2012—An experimental melanoma drug may be beneficial for patients not eligible for targeted therapies.

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Health and Medicine Reporter Research


Risk of secondary tumors from melanoma drug studied

Mar. 23, 2012—A new study offers clues on why melanoma patients who are treated with oral drugs inhibiting the BRAF gene are at increased risk for developing secondary skin cancers.

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Health and Medicine Research


New melanoma drug nearly doubles survival in majority of patients

Feb. 23, 2012—Investigators from Vanderbilt-Ingram Cancer Center and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

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Health and Medicine Research