Blood
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Researchers clarify role of blood cell mutations in disease
Vanderbilt researchers have developed a new method to analyze mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells. Read MoreFeb 2, 2023
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How Epo action is ‘enhanced’
The hormone erythropoietin (Epo) controls red blood cell production and synthetic forms of Epo treat multiple disorders. New Vanderbilt research details how Epo works. Read MoreJul 24, 2017
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Risk of death in sickle cell disease
Two factors commonly used to evaluate patients with sickle cell disease are associated with each other and can predict increased mortality, Vanderbilt researchers have discovered. Read MoreFeb 22, 2017
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Hhex on cancer
A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production. Read MoreJul 13, 2015
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Kids more likely to react to blood transfusions
Pediatric patients have a significantly higher incidence of transfusion reactions compared to adults, according to a study by Vanderbilt University researchers. Read MoreMay 4, 2015
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Streptococcus virulence involves three-step plasminogen binding
Researchers at Vanderbilt have shown for the first time how a component of streptococci A and C bacteria helps spread the virus so rapidly through the body. Read MoreMar 20, 2015
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Linking oxygen, iron and red blood cells
The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read MoreFeb 6, 2013
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Bid protein guards blood cells against stress
A protein normally known to promote cell death found to encourage survival of blood forming cells. Read MoreOct 25, 2012
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Targeting post-transplant diabetes
Targeting diabetes that develops after a stem cell transplant may help moderate graft-vs.-host disease, an adverse effect of the procedure, and improve outcomes. Read MoreApr 12, 2012