Bipolar Disorder

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders. Read More

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting. Read More

Mimi Baird had not seen or heard from her father since the Harvard-trained physician, tormented by severe bipolar disease, walked away from his family when she was 5 years old. Then, when she was in her mid-50s, a mysterious box arrived at her door. Read More

The transgenic mouse, into which was inserted a rare human genetic variation in the dopamine transporter, could lead to improvements in the diagnosis and treatment of these all-too-common brain disorders. Read More

Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder. Read More

Vanderbilt University investigators for the first time have linked a non-inherited, de novo mutation in the dopamine transporter to autism spectrum disorder (ASD). Read More

Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read More

Bipolar depression and schizophrenia share patterns of changes in neurons that regulate information flow, new research shows. Read More

RSV prefers stressed cells “Stress granules” – globs of proteins and RNAs – form inside cells in response to environmental stressors and are thought to regulate protein production. Several viruses induce stress granule formation, but the function of these structures during virus replication is not well understood. James Crowe Jr.,… Read More