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Biological Psychiatry Archives

Brain connections in schizophrenia

Mar. 9, 2018—Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia.

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Study helps map signaling system in brain linked to ASD

Feb. 8, 2018—Researchers at Vanderbilt University have worked out part of the “wiring diagram” of a signaling system in the brain that has been linked to autism spectrum disorder (ASD).

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Regulating anxiety in the brain

Apr. 28, 2017—Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

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Probing drug abuse circuitry

Nov. 4, 2016—Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders.

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Brain circuitry in psychosis

Aug. 21, 2015—Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions.

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Skin biopsy to diagnose depression?

Aug. 29, 2014—It may be possible to use skin cells as biomarkers to diagnose and manage depression.

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Antioxidants promising for rare disorder

Feb. 6, 2014—The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development.

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Memory intact in early psychosis

Feb. 16, 2012—Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities.

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