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beta cells Archives

Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Making human beta cells reproduce

Dec. 8, 2016—A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.

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Fighting type 2 diabetes with FGF1

Nov. 18, 2015—The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.

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New therapeutic target for diabetes

Aug. 20, 2015—The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.

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Boosting beta cells in diabetes

Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

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CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

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Searching for beta cell stimulators

Jan. 13, 2014—Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

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Pancreas cells full of potential

Feb. 18, 2013—Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

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Beta cell imaging could help spot diabetes earlier

May. 23, 2012—Vanderbilt researchers have developed a biomarker for beta cells that could make it easier to detect diabetes earlier.

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Pumping up the pancreas in pregnancy

Jan. 20, 2012—A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

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Health and Medicine Reporter Research