American Journal Of Physiology
-
Protein dynamics in the beating heart
To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read MoreDec 16, 2019
-
Potassium balance and glaucoma
Vanderbilt Eye Institute researchers have discovered that an imbalance in the ionic environment of retinal ganglion cells may contribute to functional impairments in glaucoma. Read MoreJul 15, 2019
-
A target to heal tiny lungs
The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth. Read MoreFeb 23, 2017
-
Making human beta cells reproduce
A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells. Read MoreDec 8, 2016
-
In search of new asthma therapies
A peptide molecule relaxes airway smooth muscle and may be a potential therapeutic for asthma that has become resistant to standard therapies. Read MoreAug 15, 2016
-
Fetal impact of antidepressants
Antidepressant use during pregnancy is common. Fetal exposure to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) is associated with the life-threatening condition PPHN (persistent pulmonary hypertension of the newborn), but a causal link has not been established. Read MoreAug 3, 2016
-
Tiny model of diabetes
Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment. Read MoreFeb 20, 2015
-
Antibiotics, fetal vessel defect linked
Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read MoreOct 15, 2014
-
Patient-derived stem cells shed light on pulmonary hypertension
Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies. Read MoreSep 16, 2014