American Heart Association

A bifunctional natural compound has been discovered with the potential to make antibiotic resistance to deadly infections less likely. Read More

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read More

Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells. Read More

Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division. Read More

Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read More

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses. Read More

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read More

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology. Read More

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. Read More

Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease. Read More

Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension. Read More

Vanderbilt investigators have now discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury. Read More

Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health. Read More

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read More

Carlos Lopez, Tina Iverson and Vsevolod Gurevich propose that a conveyer belt best describes the mechanism by which cellular signals are handed off from enzyme to enzyme in the brain. Read More

The hidden lives of medical biomarkers are the focus of a recent study in Nature Communications by Jonathan Mosley. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

Vanderbilt University Medical Center (VUMC) has been selected by the American Heart Association (AHA) to participate in a six-member research network to advance treatment and prevention of atrial fibrillation (AFib), an irregular heart rate that increases the risk of stroke and other heart-related complications. Read More