American Cancer Society

Kathleen DelGiorno, assistant professor of cell and developmental biology, has received a Research Scholar Award from the American Cancer Society. The award will fund research into potential therapies against pancreatic cancer, the third-leading cause of cancer-related deaths in the United States, which is forecast to become the second-leading cause by 2030. Read More

Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection. Read More

The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells. Read More

Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read More

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization. Read More

Researchers in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center have received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition. Read More

Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered. Read More

Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets. Read More

A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read More

A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found. Read More

Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior. Read More

A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses. Read More

A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy. Read More

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis. Read More

Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer. Read More

Amid the intense discussions around head and neck cancer (HNC) treatment and survivorship planning, sexuality — an important quality of life issue — may understandably not be discussed. When and in what manner do patients with HNC want to talk about the impact the disease may have on their sexuality? Read More

Vanderbilt University School of Nursing (VUSN) Assistant Professor Jie Deng, Ph.D., R.N., has been awarded a $789,000 research scholar grant by the American Cancer Society to develop and test a self-care program for head and neck cancer survivors diagnosed with secondary lymphedema and fibrosis (LEF). Read More

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read More

Aron Parekh, Ph.D., assistant professor of Otolaryngology, has received a four-year, $790,000 Research Scholar Grant from the American Cancer Society to further his research into the mechanical and biological properties of cancer cells and the methods by which they leave the initial tumor and spread or metastasize to other parts of the body. Read More

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read More