Alzheimer’s Disease

Post-intensive care syndrome includes yearslong cognitive, physical, mental and socioeconomic impairments. Led by world renowned experts in ICU recovery care at Vanderbilt, this transinstitutional study will facilitate best practice development of comprehensive care programs for patients and caregivers after leaving ICU. Read More

A Vanderbilt study of genetic risks for cognitive impairment later in life uses data from 32,426 research participants ages 60 and older to elaborate these risks across sex and across the intersection of sex and race. Read More

Warren Center for Neuroscience Drug Discovery lead researchers discover a therapy that may treat memory loss and slow the progression of Alzheimer’s disease. Read More

Biomedical engineering doctoral student Sarah Goodale has been awarded a National Institute on Aging Transition to Postdoc Fellowship for her proposed work on investigating fatigue and sleep disturbance symptoms in Alzheimer’s Disease and their relationship with functional and structural properties of the brain and intellectual decline. The National Institutes of Health NIA F99/K00 award supports... Read More

Reported June 13 in Neurology, an Alzheimer’s disease risk study from Vanderbilt University Medical Center measures significantly reduced risk associated with healthy lifestyles, including non-smoking, leisure-time exercise, low-to-moderate alcohol consumption, adequate sleep and healthy diet. Read More

Prothena and the Warren Center for Neuroscience Drug Discovery have entered into a collaborative research agreement to develop new small molecule therapeutics for the treatment of Alzheimer’s disease in individuals with Down syndrome. Read More

Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology. Read More

The third annual Vanderbilt Alzheimer’s Disease Research Day will be Thursday, March 31, from 8 a.m. to 6 p.m. at Vanderbilt University School of Nursing. The campus-wide academic event will showcase Alzheimer’s disease and related dementia research from multiple clinical and basic science departments across campus. Read More

The Vanderbilt Kennedy Center is teaming up with the Down Syndrome Association of Middle Tennessee to host a virtual workshop on “Risks of Alzheimer's Disease in Adults with Down Syndrome and Introduction to a Research Study.” The discussion will take place on Tuesday, Jan. 25, from 2 to 3 p.m. CT. Read More

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19. Read More

Professor of Electrical and Computer Engineering Bennett Landman has received a $2.6 million NIH grant to improve the understanding of structural changes in the brains of people who have Alzheimer’s disease. Read More

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read More

The Vanderbilt Kennedy Center and the Down Syndrome Association of Middle Tennessee will co-sponsor a webinar, “Risks of Alzheimer's Disease in Adults with Down Syndrome and Introduction to a Research Study,” on Monday, March 29, from 7 to 8 p.m. CT. Read More

Christos Constantinidis has been appointed professor in the Department of Biomedical Engineering beginning Jan. 1, 2021. At Vanderbilt, he also will be a member of the university’s Brain Institute and the Vision Research Center. Read More

Changes in connectivity in the brain’s white matter may be a novel neuroimaging biomarker for assessing Alzheimer’s disease progression. Read More

Behavioral and systems neuropharmacologist Jerri Rook is recognized by the Alzheimer’s Drug Discovery Foundation with the Goodes Prize to continue her work in Alzheimer’s disease research. Read More

Angela Jefferson, PhD, professor of Neurology and director of the Vanderbilt Memory and Alzheimer’s Center, has been awarded a $3.7 million, three-year grant from the National Institute on Aging (NIA) to support establishment of a prospective NIA-funded Alzheimer’s Disease Research Center (ADRC) at Vanderbilt University Medical Center. Read More

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read More

A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease. Read More

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions. Read More