Alzheimer’s

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read More

Led by Craig W. Lindsley, Vanderbilt drug discovery experts set out to develop a backup drug candidate to improve memory loss in people with Alzheimer’s disease. Read More

The Vanderbilt Memory and Alzheimer's Center hosted its fifth Annual Vanderbilt Alzheimer’s Disease Research Day on April 10 with the theme of “big data.” Aside from presentations from faculty from across campus and the School of Medicine Basic Sciences, the day featured data blitzes, a keynote presentation, and a poster reception with more than 45 posters. Read More

Ethan Lippmann, associate professor of chemical and biomolecular engineering and biomedical engineering, has won a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative (CZI) to create a more effective way for the immune system to fight against neurodegenerative diseases like Alzheimer’s. Read More

Experts in research on Alzheimer’s disease and related dementias share their latest findings at the 2023 Alzheimer’s Association International Conference. Nik Lampe, postdoctoral researcher, was awarded a grant to examine the social and medical factors influencing ADRD using data from VUSNAPS. Read More

Vanderbilt engineering professor Justus Ndukaife is leading innovative research that more effectively traps nanosized extracellular vesicles and particles to analyze their roles in cancer, and neurodegenerative diseases. Read More

SNARE proteins determine how tiny membrane pouches called vesicles fuse with different cellular compartments to transport cargo and organize cells. How cells correctly target individual SNAREs to their destination is poorly understood, but the laboratories of Todd Graham, Jason MacGurn and Lauren Jackson recently published a paper uncovering part of the process that controls this compartmentalization.   Read More

Reported June 13 in Neurology, an Alzheimer’s disease risk study from Vanderbilt University Medical Center measures significantly reduced risk associated with healthy lifestyles, including non-smoking, leisure-time exercise, low-to-moderate alcohol consumption, adequate sleep and healthy diet. Read More

Lucie Kalousová, assistant professor of medicine, health and society and of sociology, has received a two-year New to the Field Award of $114,000 from the Alzheimer’s Association. Corey Bolton, a postdoctoral fellow at the Vanderbilt Memory and Alzheimer’s Center, has been awarded a two-year, $140,000 Alzheimer’s Association Clinician Scientist Fellowship. Read More

Vanderbilt University’s RASR Laboratory in the Department of Chemistry is seeking African American individuals, age 40 and older, who reside in Nashville and the surrounding communities to participate in a one-time, two-hour focus group on Wednesday, Feb. 23, from 6 to 8 p.m. to review short videos and materials and provide feedback. Read More

Behavioral and systems neuropharmacologist Jerri Rook is recognized by the Alzheimer’s Drug Discovery Foundation with the Goodes Prize to continue her work in Alzheimer’s disease research. Read More

The ways certain proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men. Read More

Staff from the Center for Cognitive Medicine will administer memory screenings and Alzheimer’s gene screenings at no cost to community members ages 60 and above. Read More

Center for Cognitive Medicine offering Alzheimer's APOE4 Gene Screening at Whole Foods on Feb. 18. Read More

The Center for Cognitive Medicine is seeking volunteers ages 65-75 who have not been diagnosed with any memory impairment and are interested in whether their genetics show they are at increased risk of Alzheimer’s disease. Read More

Interested in the treatments and prevention of Alzheimer's disease? The Center for Cognitive Medicine is hosting an open house and screening event on Sept. 7. Read More

The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system. Read More

The Center for Cognitive Medicine at Vanderbilt University Medical Center in partnership with the Generation Program will be offering ApoE4 Alzheimer’s Gene Screening on Friday, August 3. Read More

Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis. Read More

Developed at Vanderbilt, VU319 is designed to precisely target a specific neuron receptor associated with cognitive function while avoiding potentially dangerous side effects. Read More