Aliquots
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Integrin curbs cancer’s spread
Cell surface molecules called integrins have been found to play an important role when cancer metastasizes. Read MoreFeb 16, 2011
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Fluorine aids gene silencing
Modifying a form of RNAs may improve their efficacy for research and medical uses. Read MoreFeb 15, 2011
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Seeing serotonin neurons in action
The Vanderbilt MRI Labs Physics / Imaging Department (Anne Rayner / Vanderbilt) Serotonin – a chemical that has roles in multiple brain functions, including mood, sleep and cognition – is manufactured by clusters of brainstem neurons gathered in the raphé nuclei. A reliable, non-invasive imaging method for assessing raphé neuron… Read MoreFeb 9, 2011
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BPA exposure tests in question
The industrial chemical BPA is found in commercial products, such as plastic water bottles. (iStock Photo) The safety of industrial chemicals bisphenol A (BPA) and alkylphenols, which are used in commercial products like plastics, has recently been called into question. Exposure to these chemicals is typically measured… Read MoreFeb 8, 2011
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Mapping obesity circuitry in brain
(Photo credit: iStock photo) In the battle of the bulge, one important battalion is a set of brain cells expressing the melanocortin-4 receptor (MC4R). Via signals from the fat-derived hormone leptin, these neurons regulate feeding behavior and fat metabolism in an attempt to regulate body weight. But how leptin influences… Read MoreFeb 7, 2011
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Aliquots – VUMC research highlights
RSV prefers stressed cells “Stress granules” – globs of proteins and RNAs – form inside cells in response to environmental stressors and are thought to regulate protein production. Several viruses induce stress granule formation, but the function of these structures during virus replication is not well understood. James Crowe Jr.,… Read MoreJan 6, 2011