AHA

In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease. Read More

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases. Read More

Heat therapy could offer a novel nonpharmacologic approach for treating the overnight hypertension that affects patients with autonomic failure. Read More

In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes. Read More

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study. Read More

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential. Read More

Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read More

Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read More

Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division. Read More

Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read More

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses. Read More

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology. Read More

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes. Read More

Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease. Read More

Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension. Read More

Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health. Read More

Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read More