Health And Medicine
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ABIM Foundation honors VUMC-authored paper
The ABIM Foundation has awarded the 2019 John A. Benson Jr., MD Professionalism Article Prize to five scholarly articles — one commentary and four research pieces — that explore physician burnout, unprofessional behavior and integrity in research. Read MoreJun 20, 2019
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Microbiome links diet to health
Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health. Read MoreJun 20, 2019
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Potential probe for early ovarian cancer
Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme. Read MoreJun 20, 2019
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Study identifies critical regulator of tumor-specific T cell differentiation
A study published June 17 in Nature offers clues as to why blocking inhibitory receptors on tumor-infiltrating T cells may not always work Read MoreJun 18, 2019
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New method tested to block chikungunya infection
Scientists are testing a new way to fight chikungunya virus that involves injecting genetic material into the bodies of infected and at-risk individuals to trigger rapid production of potent, virus-neutralizing antibodies. Read MoreJun 14, 2019
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Study seeks to expand treatment options for rare airway disease
Idiopathic subglottic stenosis is an unexplained narrowing of the windpipe just below the vocal cords. The disease is progressive, slowly affecting the patient’s ability to breathe, and can be fatal due to airway obstruction if left untreated. Read MoreJun 14, 2019
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Cardiac toxicity risk factors identified with relapsed multiple myeloma therapy
More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in the Journal of Clinical Oncology. Read MoreJun 14, 2019
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Quick DNA test for malaria drug resistance is life-saver, holds promise for other diseases
Doctors formerly had to extract the malaria parasite’s DNA first, virtually impossible to do in rural, low-resource areas. Read MoreJun 12, 2019
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Steroid binding to metabolic enzyme
Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer. Read MoreJun 12, 2019
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Cell-cell signals in developing heart
Scott Baldwin and colleagues have discovered early signaling events during heart development, findings that could guide cell replacement therapies for heart disease. Read MoreJun 10, 2019
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VUMC joins international effort to speed vaccine development
VUMC has joined an international effort to streamline and accelerate development of vaccines and other treatments against a growing worldwide surge of deadly and debilitating viral infections. Read MoreJun 6, 2019
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Mouth health and colorectal cancer
Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC. Read MoreJun 6, 2019
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Treating core Rett syndrome symptoms
A new study published in Neurology reports the drug trofinetide has proven safe and effective in treating core symptoms of Rett syndrome in female children and adolescents. Read MoreJun 6, 2019
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Study sheds light on importance of comprehension when obtaining consent
A study from Vanderbilt’s Center for Biomedical Ethics and Society is bringing renewed focus on the concept of comprehension of informed consent for research purposes. Read MoreJun 6, 2019
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Study details regulation of a multi-drug transporter
Vanderbilt University researchers have discovered how a protein pump distinguishes between chemicals that it will expel from a cell and inhibitors that block its action. The new findings could guide the development of more efficient inhibitors to prevent cancer cell resistance to chemotherapy. Read MoreMay 30, 2019
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Inaugural Alzheimer’s Disease Research Day draws crowd for talks, posters, data blitzes
Vanderbilt's inaugural Alzheimer’s Disease Research Day drew more than 100 attendees to hear faculty lectures on subjects ranging from diet to brain modeling, take in short “data blitzes” on individual areas of research, and visit a 35-station poster session. Read MoreMay 28, 2019
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Flu’s “hidden target” may lead to universal vaccine: study
The flu mutates so quickly that we need a new vaccine every year, but Vanderbilt scientists have found a vulnerable part of the virus that doesn't mutate as much. Read MoreMay 16, 2019
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Vanderbilt team determining how seasonal light for pregnant moms affects offspring’s mental health
Seasonal light exposure during pregnancy had effects on serotonin and depression that persisted into adulthood in mice. Read MoreMay 14, 2019
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Dynamic basement membranes
Basement membranes are important structural and functional components of tissues. New research provides insight into how they repair themselves. Read MoreMay 9, 2019
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Blueprint for rebuilding the heart
New findings may speed progress toward programming cells to rebuild damaged hearts more quickly. Read MoreMay 9, 2019