Health And Medicine
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Potential second-line melanoma treatment identified
A study led by Anna Vilgelm, MD, PhD, and Ann Richmond, PhD, has identified a possible second-line treatment for melanoma patients. Read MoreAug 15, 2019
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Protein’s role in inflammation-related cancer studied
Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer. Read MoreAug 15, 2019
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REDCap data management tool reaches million user mark
Fifteen years after it was launched, REDCap, Vanderbilt University’s research data management tool, has reached 1 million users throughout the world. Read MoreAug 15, 2019
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All of Us Research Program Takes Aim at Precision Population Health
Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people. All Read MoreAug 14, 2019
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Meet the alpacas that are helping researchers who study autism, Alzheimer’s and cancer
Written by Heidi Hall Alpacas aren’t the typical animals that drivers spot as they wind their way through rural Tennessee, but there’s a happy herd of them outside Waverly, where they eat the finest pellets, walk up and down a scenic hill and potentially save lives. They’re owned by… Read MoreAug 13, 2019
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Host-microbe interactions in the gut
Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health. Read MoreAug 13, 2019
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Pancreatic cancer clue
Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer. Read MoreAug 12, 2019
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A probiotic treatment for obesity?
Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases. Read MoreAug 8, 2019
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New window on fibrosis
A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases. Read MoreAug 8, 2019
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Cellular engines of wound repair have distinct roles
Vanderbilt investigators have now discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury. Read MoreAug 8, 2019
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Low-level alcohol use increases miscarriage risk
Women who consume alcohol during pregnancy — even in small amounts — have a 19% greater risk of miscarriage than women who don’t use alcohol. Read MoreAug 8, 2019
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Shu, Zheng receive Vietnam’s top honor for foreign scientists
The Vietnamese Ministry of Health has awarded two Vanderbilt epidemiologists the Memorabilia Medal “For the People’s Health” in appreciation of their contributions in helping the nation establish a population-based research program for cancer, diabetes and other non-communicable diseases. Read MoreAug 1, 2019
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Grant bolsters research on myelodysplastic syndromes
Michael Savona, MD, has received a competitive grant to develop therapies for patients with myelodysplastic syndromes. Read MoreAug 1, 2019
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Intestinal immune cell interactions
Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases. Read MoreJul 30, 2019
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New role for microtubules in diabetes
Microtubules, part of the cell's cytoskeleton, regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes. Read MoreJul 29, 2019
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Study ‘ignites’ link between genes and drug response
A national study is seeking to determine whether genetic testing can help physicians choose the best drugs for their patients to relieve pain and depression. Read MoreJul 25, 2019
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Team’s study reveals details of new DNA repair pathway
Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity. Read MoreJul 25, 2019
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Sex differences in kidney injury
Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor. Read MoreJul 25, 2019
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Defective transporter linked to autism
A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder. Read MoreJul 24, 2019
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Encephalitis identified as rare toxicity of immunotherapy treatment
Researchers are chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies. Read MoreJul 22, 2019