Health And Medicine
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Discovery offers insight for development of cancer therapies targeting mutant p53
The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation. Read MoreSep 2, 2021
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Ask an Expert: Is the COVID-19 vaccine safe for pregnant women?
Alexandra Speros, instructor in clinical nursing, midwifery and primary care, explains the latest expert guidance that encourages pregnant women to get the vaccine at any stage of their pregnancy. Read MoreAug 30, 2021
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Research Snapshot: Novel finding shows that brain cells conduct antidepressant action even in the absence of activity
Even in the absence of brain activity, nerve cells can turn on gene expression that is important for antidepressant effects. This novel finding from Lisa Monteggia gives researchers a more fundamental understanding of the brain’s mechanistic function for better therapeutics. Est. reading time: 2.5 mins. Read MoreAug 30, 2021
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Ask an Expert: Who does the vaccine protect?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, reminds us the reasons to get vaccinated. Read MoreAug 24, 2021
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Ask an Expert: Is data about deaths after vaccination valid?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, explains how signals on deaths after COVID-19 is collected and interpreted. Read MoreAug 24, 2021
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Ask an Expert: What do we know about the third dose option of the COVID-19 vaccine?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, shares information about the third dose of the COVID-19 vaccine, applicable to people with moderate to severe immunocompromise. Read MoreAug 24, 2021
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Ask an Expert: What do we know about booster shots?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, shares what we know about COVID-19 booster shots. Read MoreAug 24, 2021
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Research Snapshot: Development of a new framework and tool for multi-drug synergy and combination
MuSyC is a technique to help researchers devise new combinations of drugs. An open-source analysis tool, it holds the promise speed such discoveries around the world. Read MoreAug 24, 2021
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COVID-19 antibody ‘cocktail’ discovered at VUMC protects chronically ill: study
A monoclonal antibody cocktail against the COVID-19 virus discovered at VUMC is the first non-vaccine modified to demonstrate the prevention of COVID-19 in a clinical trial of more than 5,000 participants. The antibody treatment could afford up to 12 months of protection from COVID-19, and preliminary laboratory findings also suggest that it can neutralize the delta variant. Read MoreAug 20, 2021
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Churchwell, Creech, Wilkins among NBJ award winners
Three leaders of the Vanderbilt University Medical Center community are among the winners of the Nashville Business Journal’s 2021 Health Care Innovation awards. Read MoreAug 19, 2021
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Team isolates antibodies that target alphaviruses
A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that prevent infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus. Read MoreAug 19, 2021
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Research Snapshot: Mosquito larvae are surprisingly complex
L.J. Zwiebel and his lab show that mosquito larvae, the age group targeted for most control programs, are far more sophisticated than previously thought. Est. reading time: 2 mins. Read MoreAug 17, 2021
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Shared antibodies may push COVID variants: study
Researchers at Vanderbilt University Medical Center have found that people recovering from COVID-19 and those vaccinated against the causative virus, SARS-CoV-2, produce identical clones, or groups, of antibody-producing white blood cells. Read MoreAug 12, 2021
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Study reveals missing link between high-fat diet, microbiota and heart disease
A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science. Read MoreAug 12, 2021
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Study identifies biomarker for breast cancer response to immunotherapy
A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research. Read MoreAug 12, 2021
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Vega selected as 2021 Vanderbilt Prize Student Scholar
Paige Vega, a Ph.D. student in the Department of Cell and Developmental Biology, has been selected as the 2021 Vanderbilt Prize Student Scholar. Read MoreAug 11, 2021
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Faculty Innovator: Daniel Fabbri demonstrates academic and entrepreneurial prowess
Professor and entrepreneur finds startup success with Vanderbilt’s spirit of collaboration and innovation. Read MoreAug 11, 2021
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Ask an Expert: When will vaccines be approved for children under 12?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, shares the latest available information on when COVID-19 vaccines will be approved for children under 12. Read MoreAug 10, 2021
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Sudden death from deep in the brain?
Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read MoreAug 9, 2021
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Aug. 18: Vanderbilt Project on Unity and American Democracy and VUMC present ‘Vaccine Hesitancy: The Politics of Public Health in Tennessee’
The Vanderbilt Project on Unity and American Democracy and Vanderbilt University Medical Center will host “Vaccine Hesitancy: The Politics of Public Health in Tennessee,” a virtual event, on Wednesday, Aug. 18, at noon CT. Read MoreAug 5, 2021