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Health and Medicine

Practice of defensive orthopaedic medicine costs U.S. $2 billion annually

Feb. 9, 2012—A Vanderbilt study suggests unnecessary costs associated with the practice of defensive medicine play a substantial role in the nation’s rising cost of health care.

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Matchmaker for clinical studies

Feb. 8, 2012—ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies.

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Tool finds connections in genome data

Feb. 8, 2012—A new analytical tool points to genes that act together to increase disease risk.

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Prostate size may help in predicting cancer severity

Feb. 3, 2012—Severity of cancer could be predicted by prostate size.

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VU researcher has personal motive for investigating malaria

Feb. 3, 2012—Vanderbilt researcher and Gabon, Africa, native is working to discover ways to kill malaria-spreading mosquitoes.

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Treatment window for genetic disorder

Feb. 1, 2012—Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests.

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Drugs reverse lung cancer cell changes

Feb. 1, 2012—Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer.

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Colorectal cancer risk related to gene’s expression

Jan. 27, 2012—Individuals who are outside the normal range of expression for the adenomatous polyposis coli (APC) gene have an increased risk of colorectal cancer, according to a study published in the January issue of Gastroenterology.

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Investigators seek clues to resistance to melanoma drug

Jan. 26, 2012—Investigators at Vanderbilt-Ingram Cancer Center and several other centers may be one step closer to finding out why some melanoma patients relapse after treatment with a promising new drug.

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Protein repairs esophageal DNA damage

Jan. 25, 2012—A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer.

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Alcohol’s molecular mediators

Jan. 23, 2012—Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.

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Studies shed new light on how nitric oxide is produced

Jan. 20, 2012—The discovery of a previously unrecognized and pivotal role of enzyme ASL in nitric oxide production could potentially lead to new therapies for babies with pulmonary hypertension.

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