Health And Medicine
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Pioneers of Discovery: Investigator seeks to debug cancer’s ‘bad software’
Beyond genetics — that’s the call Oliver McDonald, M.D., Ph.D., heard during the year between college and medical school he spent in a lab at St. Jude Children’s Research Hospital in Memphis. Read MoreJan 9, 2014
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Young children engage in physical activity in short spurts; preschoolers take 11 hours to attain daily exercise levels
Preschool-aged children require the majority of their waking day to achieve their recommended daily physical activity, a Vanderbilt study published in Obesity found. Read MoreJan 8, 2014
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Vanderbilt study shows suicide risk doesn’t differ in children taking two types of commonly prescribed antidepressants
A new Vanderbilt University Medical Center study shows there is no evidence that the risk of suicide differs with two commonly prescribed antidepressants prescribed to children and adolescents. Read MoreJan 7, 2014
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Ancient chemical bond may aid cancer therapy: study
A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the “dawn of the animal kingdom” could lead to new therapies for cancer and other diseases. Read MoreDec 19, 2013
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Bariatric surgery’s metabolic impact to be explored
Vanderbilt University researchers have received a two-year, $1.2 million grant from the National Institutes of Health (NIH) to study a mouse model of the metabolic and hormonal changes caused by bariatric surgery. Read MoreDec 19, 2013
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VU study identifies new gene fusions in melanoma
Cancer researchers, led by investigators at Vanderbilt-Ingram Cancer Center, have identified two novel gene fusions in melanoma that may be responsive to existing cancer therapies. Melanoma is the most deadly form of skin cancer. Read MoreDec 19, 2013
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Targeting tumor “supply lines”
A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies. Read MoreDec 18, 2013
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Cancer drug enhances cognition
The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women. Read MoreDec 16, 2013
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Manager of mitotic stress
The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis. Read MoreDec 13, 2013
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Study to explore new technologies to connect doctors, patients outside medical settings
A five-year study to explore new technologies that automate patient care outside of hospitals and doctors’ offices will identify ways technology can provide real-time feedback and guidance to patients and to alert care coordination teams before health issues escalate. Read MoreDec 12, 2013
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Therapeutic target for gastric cancer
A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read MoreDec 12, 2013
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Proton transfer powers multidrug resistance: study
Vanderbilt University researchers and their Belgian colleagues have discovered the mechanism behind a multidrug transporter. Their findings, posted this week by Nature Chemical Biology, could lead to new treatments for multidrug resistant bacterial infections. Read MoreDec 12, 2013
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VU study points to central regulator of neuron development
Developmental biologist Chin Chiang, Ph.D., and his colleagues have discovered that Purkinje neurons in the cerebellum act as central regulators of neuronal development. Read MoreDec 12, 2013
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GE grant expands global medical outreach efforts
Vanderbilt University has received a $3 million grant from the GE Foundation’s Developing Health Globally program to fund international medical education and research in Kenya and other low-resource regions of the world. Read MoreDec 12, 2013
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Penicillin equally effective as ‘big gun’ antibiotics for treating less severe childhood pneumonia, Vanderbilt study shows
Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with “big gun” antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin. Read MoreDec 9, 2013
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Pioneers of Discovery: Investigator explores how cells decide what’s on surface
Jason MacGurn, Ph.D., a new assistant professor of Cell and Developmental Biology at Vanderbilt, is studying how cells make decisions about the protein composition of the cell surface. Read MoreDec 5, 2013
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Brain research foundation lauds VU’s Winder, Park
Vanderbilt University’s Danny Winder, Ph.D., professor of Molecular Physiology and Biophysics, is among 15 scientists nationwide to receive NARSAD Distinguished Investigator Grants this fall for their “cutting-edge” research. Read MoreDec 5, 2013
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Predictor of prostate cancer outcomes identified
Researchers at Vanderbilt University Medical Center and the University of Alberta in Canada have identified a biomarker for a cellular switch that accurately predicts which prostate cancer patients are likely to have their cancer recur or spread. Read MoreDec 5, 2013
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First-ever study uses EMRs to spot new disease associations
Vanderbilt University Medical Center researchers and co-authors from four other U.S. institutions from the Electronic Medical Records and Genomics (eMERGE) Network are repurposing genetic data and electronic medical records to perform the first large-scale phenome-wide association study (PheWAS), released today in Nature Biotechnology. Read MoreDec 5, 2013
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VU researchers report G protein advancement that could lead to more effective drugs
Thanks in part to a computer program named “Rosetta,” Vanderbilt University researchers are closer to understanding how the ubiquitous G protein is activated – a discovery that could lead to the design of more specific and effective drugs. Read MoreDec 2, 2013