Health And Medicine
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E-records shed light on drug response
Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read MoreMar 31, 2014
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Mapping brain circuitry
Vanderbilt investigators have used two types of neuroimaging to establish a “map” of connections for a brain region important in anxiety and addiction. Read MoreMar 28, 2014
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Gut woes of preemies focus of microbiome effort
A multidisciplinary team of microbiome researchers at Vanderbilt University is shedding light on necrotizing enterocolitis (NEC), a disease of prematurity that kills hundreds of babies and costs the U.S. health care system an estimated $5 billion a year. Read MoreMar 27, 2014
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Grant bolsters patient-centered outcomes research
Patient-centered outcomes research is the focus of a $3.3 million, five-year, institutional K12 training grant awarded to Vanderbilt University Medical Center by the Agency for Healthcare Research and Quality (AHRQ). Read MoreMar 27, 2014
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Study links stem cell gene to prostate cancer susceptibility
A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found. Read MoreMar 27, 2014
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Flu boosts pneumococcal colonization
Influenza and parainfluenza infections – but not other respiratory viruses – increase the risk of acquiring pneumococcal bacteria, the most common cause of severe pneumonia. Read MoreMar 27, 2014
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Study team able to disrupt ‘building blocks’ of behavior
Researchers at Vanderbilt have been able to alter mouse behavior by silencing gene expression in interneurons, distinct populations of nerve cells that are the main regulators of brain circuits. Read MoreMar 20, 2014
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Small molecule protects kidney filter
A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier. Read MoreMar 19, 2014
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Delirium increases long-term disability
Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read MoreMar 17, 2014
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Protein boosts retinal neuron survival
An ion channel protein called TRIPV1 helps retinal neurons survive the elevated eye pressure associated with glaucoma. Read MoreMar 14, 2014
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‘Missing link’ may spur new brain disorder drugs
Researchers at the Scripps Research Institute in San Diego and Vanderbilt University have discovered a “missing link” in the structure of a transmembrane receptor that could lead to new treatments for autism, schizophrenia, Parkinson’s disease and Alzheimer’s disease. Read MoreMar 13, 2014
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Viral illness may spur ‘standing up’ disorder
Circulating “autoantibodies” possibly triggered by a viral illness may contribute an abnormally rapid heart rate or tachycardia upon standing that affects 500,000 Americans, mostly young women, according to researchers at the University of Oklahoma and Vanderbilt University. Read MoreMar 13, 2014
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A new way to target cancer-driver Ras
Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way. Read MoreMar 13, 2014
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Diabetes researchers track cells’ ability to regenerate
Vanderbilt University scientists have found evidence that the insulin-secreting beta cells of the pancreas, which are either killed or become dysfunctional in the two main forms of diabetes, have the capacity to regenerate. Read MoreMar 13, 2014
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Multi-center effort targets lethal Ebola, Marburg viruses
Vanderbilt University researchers are collaborating in a multi-center, federally-funded project to develop ways to treat and prevent the highly lethal Ebola and Marburg virus infections. Read MoreMar 6, 2014
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Discovery sheds new light on marijuana’s anxiety relief effects
An international group led by Vanderbilt University researchers has found cannabinoid receptors, through which marijuana exerts its effects, in a key emotional hub in the brain involved in regulating anxiety and the flight-or-fight response. Read MoreMar 6, 2014
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Web tool speeds pulmonary hypertension discovery
The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis. Read MoreMar 5, 2014
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Dismantling staph’s drug resistance
Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin. Read MoreMar 3, 2014
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Imaging guides Alzheimer gene search
Using imaging data, Vanderbilt researchers discovered an association between a gene pair and brain changes in Alzheimer’s disease. Read MoreFeb 28, 2014
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Probing the pathogenesis of leukemia
A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia. Read MoreFeb 27, 2014