Health And Medicine
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Gene mutation linked to breast cancer therapy resistance
A group of Vanderbilt-led investigators has identified a new gene mutation that may explain why some breast cancer patients do not respond to anti-hormone therapy. Read MoreNov 20, 2014
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Team finds drug repurposing signal in e-health records
With research and development costs for many drugs reaching well into the billions, pharmaceutical companies want more than ever to determine whether their drugs already at market have any hidden therapeutic benefits that could warrant putting additional indications on the label and increasing production. Read MoreNov 20, 2014
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Tindle to direct Tobacco Research and Treatment
November is well-known as Lung Cancer Awareness Month. It is also the month that highlights awareness of less publicized forms of cancer including pancreatic cancer and stomach cancer. Read MoreNov 20, 2014
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Study finds national decline in one type of serious heart attack
The most emergent form of heart attacks is decreasing nationwide, but this declining incidence could affect emergency departments’ quality and timeliness of care. Read MoreNov 20, 2014
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Receptor discovery shines new light on appetite regulation
A receptor in the brain that regulates appetite and body weight has now been found in L cells, key regulatory cells in the gut, providing the pharmaceutical industry with a novel drug target for both obesity and diabetes, a Vanderbilt University-led research team reported this week. Read MoreNov 20, 2014
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More breast cancer patients opting for mastectomy, Vanderbilt study finds
Far more breast cancer patients are choosing to undergo mastectomy, including removal of both breasts, instead of choosing breast conservation surgery even when they have early stage disease that is confined to one breast, a Vanderbilt study shows. In the past decade, there have also been… Read MoreNov 19, 2014
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Vanderbilt’s neurovascular chip project moves into new phase
Vanderbilt researchers will play a key role in the second phase of the federal "tissue chip for drug screening" program. Read MoreNov 18, 2014
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Grant bolsters inguinal hernia repair research
Martin Blakely, M.D., M.S., has been awarded a $3 million federal grant for a multi-center, multi-disciplinary study to examine the safety outcomes of early versus later inguinal hernia repair for premature infants. Read MoreNov 13, 2014
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Standardized social, behavioral data key to EHR success
In recent years the federal government has used financial incentives and penalties to promote use of electronic health records (EHR), but in these regulations the issue of EHR data interoperability — that is, data standardization — has been left largely unresolved, dimming prospects for data exchange, population health surveillance and systematic improvement across health networks. Read MoreNov 13, 2014
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Physical therapy helps ease vocal muscle imbalances
For singers who suddenly can’t hit their high notes or call center workers who develop pain while speaking, physical therapy may offer new treatment solutions. Read MoreNov 13, 2014
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New insight on oral cancer culprits
A new mouse model offers insight into the signaling pathways that control oral cancers – and a platform for testing anticancer therapeutics. Read MoreNov 12, 2014
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Protein “pockets” help ID cancer genes
Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response. Read MoreNov 11, 2014
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Overactive stress response in obesity
An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial. Read MoreNov 7, 2014
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Immune cell activity and melanoma
The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells. Read MoreNov 6, 2014
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Optogenetics sheds new light on brain’s behavior modulators
A new light-based technology is allowing scientists to peer deep into the brain and alter animal behavior with the “flip of a switch.” Read MoreNov 6, 2014
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Diabetes effort aims to boost function of insulin-producing cells
Vanderbilt University is part of a national effort to improve diabetes treatment by developing strategies for proliferating, regenerating and improving the function of insulin-producing beta cells in the pancreatic islets. Read MoreNov 6, 2014
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Off Limits: Doctors are working to research and treat the increasing number of Americans with severe food allergies
According to Food Allergy Research and Education, about 1.5 million Americans have food allergies. They affect 1 in every 13 children under 18 in the U. S.—or about two in every classroom. Those who have them must approach food with a great deal of caution. Read MoreNov 5, 2014
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Elderly face no added risk from cosmetic surgery: study
Senior citizens are at no higher risk for complications from cosmetic surgery than younger patients, according to a recent study by plastic surgeons at Vanderbilt University Medical Center. Read MoreOct 30, 2014
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Potential therapy for postpartum breast cancer investigated
Nearly 25 percent of all breast cancers among premenopausal women occur within two to five years following a pregnancy. Read MoreOct 30, 2014
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NIH grant spurs diabetic nephropathy research
Diabetic nephropathy, or kidney disease caused by diabetes, is a major source of morbidity and mortality. In the United States, more than 30 percent of patients receiving either dialytic therapy or renal transplantation have end stage renal disease as a result of diabetic nephropathy. Read MoreOct 30, 2014