Health And Medicine
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Team seeks to create genetic map of worm’s nervous system
A complete map of gene expression for the worm may help address broad questions in neuroscience about how gene expression programs establish diverse sets of neurons and how genetic differences contribute to neuronal function in healthy and disease conditions. Read MoreDec 7, 2018
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Team spots clue to rare lung and kidney diseases
Research led by Billy Hudson has identified an antibody associated with pulmonary-renal syndrome, a rare autoimmune condition. Read MoreDec 7, 2018
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Ethnicity proves reliable indicator of what microbes thrive in the gut
Changing the gut microbiome to beat illness really does hold great potential, but first scientists must answer what constitutes a healthy gut microbiome and in whom. Read MoreDec 4, 2018
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Beta cell biomarker findings may speed diabetes research
Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes. Read MoreNov 30, 2018
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Lung cancer survival signal
New research by Jonathan Lehman and Pierre Massion have identfied a bioimarker that suggests poor prognosis for small-cell lung cancer, as well as potential target for new therapies. Read MoreNov 30, 2018
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Ethics study explores precision medicine’s risks, rewards
Results of the study suggest the prospect of an array of individual and societal benefits to personalized medicine, as well as risks for physical, dignitary, group, economic, psychological and legal harms, many of which may have been over-emphasized or overlooked in the literature. Read MoreNov 30, 2018
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NEI grants help bolster glaucoma research efforts
Tonia Rex and David Calkins were recently awarded National Eye Institute grants totaling $6.8 million over five years to develop new treatments for optic neuropathies and glaucoma, the leading cause of irreversible blindness. Read MoreNov 30, 2018
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Green tea and diabetes
A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism. Read MoreNov 30, 2018
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Analyzing single-cell landscapes
Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies. Read MoreNov 30, 2018
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Parsing diabetic skin infections
People with diabetes may be prone to more skin infections due to an overabundance of a compound that controls inflammation in the body. Read MoreNov 30, 2018
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Five faculty elected AAAS fellows
Five Vanderbilt University faculty members have been elected new fellows of the American Association for the Advancement of Science, the world’s largest general scientific society. Read MoreNov 27, 2018
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Immunotherapies linked to specific heart complications
In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have identified several of the conditions that arise and have determined that they usually appear early in treatment. Read MoreNov 16, 2018
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Benefits of smoking cessation take time: study
It can take up to 16 years for a smoker's body to return to the same state of health as a non-smoker, but significant benefits do begin to appear right away, according to new research by Meredith Duncan. Read MoreNov 15, 2018
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Vanderbilt study suggests way to prevent rare lung disease
Pulmonary hypertension may be treated by targeting a bone marrow cell that normally promotes the growth of new blood vessels, according to new research by David Merryman. Read MoreNov 15, 2018
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Low health literacy associated with early death for cardiovascular patients
Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to new research by Lindsay Mayberry and Sunil Kripalani. Read MoreNov 8, 2018
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Evading cell death
Susan Wente and Laura Glass have developed an experimental cell culture model system to investigate the link between stress granules and cell resistance to toxic stress, which could lead to new avenues for treating cancer treatment resistance. Read MoreNov 8, 2018
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Vitamin C protects brain from seizures
Fiona Harrison and colleagues have found evidence that Vitamin C can help protect brains against seizures and cognitive decline in Alzheimer’s disease. Read MoreNov 8, 2018
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Novel methods to treat glaucoma
Rebecca Sappington and colleagues have found that increasing cGMP — part of a signaling pathway that was previously found to regulate intraocular pressure — protects retinal ganglion cells affected by glaucoma. Read MoreNov 8, 2018
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Obesity negates beneficial drug effects
Lin Zhu and Rob Stafford have found that obesity interferes with cholesterol-improving CTEP inhibitors. Read MoreNov 8, 2018
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Team’s findings show glutamine metabolism affects T cell signaling
Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read MoreNov 1, 2018