Health And Medicine
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NEI grants help bolster glaucoma research efforts
Tonia Rex and David Calkins were recently awarded National Eye Institute grants totaling $6.8 million over five years to develop new treatments for optic neuropathies and glaucoma, the leading cause of irreversible blindness. Read MoreNov 30, 2018
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Green tea and diabetes
A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism. Read MoreNov 30, 2018
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Analyzing single-cell landscapes
Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies. Read MoreNov 30, 2018
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Parsing diabetic skin infections
People with diabetes may be prone to more skin infections due to an overabundance of a compound that controls inflammation in the body. Read MoreNov 30, 2018
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Five faculty elected AAAS fellows
Five Vanderbilt University faculty members have been elected new fellows of the American Association for the Advancement of Science, the world’s largest general scientific society. Read MoreNov 27, 2018
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Immunotherapies linked to specific heart complications
In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have identified several of the conditions that arise and have determined that they usually appear early in treatment. Read MoreNov 16, 2018
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Benefits of smoking cessation take time: study
It can take up to 16 years for a smoker's body to return to the same state of health as a non-smoker, but significant benefits do begin to appear right away, according to new research by Meredith Duncan. Read MoreNov 15, 2018
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Vanderbilt study suggests way to prevent rare lung disease
Pulmonary hypertension may be treated by targeting a bone marrow cell that normally promotes the growth of new blood vessels, according to new research by David Merryman. Read MoreNov 15, 2018
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Low health literacy associated with early death for cardiovascular patients
Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to new research by Lindsay Mayberry and Sunil Kripalani. Read MoreNov 8, 2018
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Evading cell death
Susan Wente and Laura Glass have developed an experimental cell culture model system to investigate the link between stress granules and cell resistance to toxic stress, which could lead to new avenues for treating cancer treatment resistance. Read MoreNov 8, 2018
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Vitamin C protects brain from seizures
Fiona Harrison and colleagues have found evidence that Vitamin C can help protect brains against seizures and cognitive decline in Alzheimer’s disease. Read MoreNov 8, 2018
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Novel methods to treat glaucoma
Rebecca Sappington and colleagues have found that increasing cGMP — part of a signaling pathway that was previously found to regulate intraocular pressure — protects retinal ganglion cells affected by glaucoma. Read MoreNov 8, 2018
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Obesity negates beneficial drug effects
Lin Zhu and Rob Stafford have found that obesity interferes with cholesterol-improving CTEP inhibitors. Read MoreNov 8, 2018
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Team’s findings show glutamine metabolism affects T cell signaling
Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read MoreNov 1, 2018
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Team seeks to identify immune response to influenza
Vanderbilt researchers led by Buddy Creech are searching for the key to lasting protection against influenza by examining naturally protecting cells found in bone marrow. Read MoreNov 1, 2018
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Mary Kay Foundation grant to bolster immunotherapy research
The grant will allow Charles Caskey to lead research into using ultrasound as an image-guided therapy for drug delivery. Read MoreOct 26, 2018
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Grant to help explore critical issues in Down syndrome
The grant will allow Kennedy Center researchers to analyze data from VUMC's Synthetic Derivative and BioVU databanks to study biomarkers associated with Down Syndrome. Read MoreOct 26, 2018
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Probing the pathology of impaired cognition
A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies Read MoreOct 26, 2018
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Grant enhances study of new chemotherapy targets
Vanderbilt chemists have been awarded $7.2 million over the next five years from the National Cancer Institute to lead an initiative to better understand how a combination chemotherapy for breast cancer targets DNA. Read MoreOct 19, 2018
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Targeting diabetic kidney disease
Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease. Read MoreOct 16, 2018