Health And Medicine
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EHRs, biobanks and Mendelian diseases
Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis. Read MoreApr 30, 2020
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Antibody finding raises hopes for Marburg, COVID-19 treatments
Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody "cocktails" to counter viral infection. Read MoreApr 30, 2020
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Transporter’s role in gut barrier
A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections. Read MoreApr 21, 2020
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Reducing stress in parents of children with autism
Parents of children with autism spectrum disorders benefited from the addition of mindfulness-based stress reduction to parent-implemented behavioral interventions. Read MoreApr 21, 2020
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‘Tuning’ cell shape for division
Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division. Read MoreApr 20, 2020
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Damage, disruption, delirium
New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients. Read MoreApr 20, 2020
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Research team awarded $9 million to study extracellular RNA in colorectal cancer
A multidisciplinary team of investigators at Vanderbilt University and Vanderbilt University Medical Center has received a program project grant from the National Cancer Institute to explore extracellular RNA in colorectal cancer. Read MoreApr 15, 2020
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Study tracks genomics of lung tumor behavior
A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. Read MoreApr 13, 2020
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Vanderbilt Health Policy COVID-19 model finds evidence of flattening curve, recommends distancing policies continue
Vanderbilt researchers find that social distancing policies have slowed the spread of COVID-19, but caution that continued distancing is needed to keep the rate of spread low, and that any future rollback of such policies must be contingent on widely available testing and contact tracing. Read MoreApr 10, 2020
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Study aims to shield health workers from COVID-19 infection
Vanderbilt University Medical Center is playing a key role in the HERO program, a national effort to establish a registry of U.S. health care workers and test whether the anti-malarial drug hydroxychloroquine will protect them, their patients and their families from COVID-19. Read MoreApr 10, 2020
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Study launched to test hydroxychloroquine as treatment for COVID-19
Vanderbilt University Medical Center is leading a clinical trial to understand if a well-known drug used for malaria and rheumatologic conditions is safe and effective in treating hospitalized adults with COVID-19. Read MoreApr 10, 2020
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Vanderbilt University Medical Center and AstraZeneca join forces to identify potential COVID-19 treatments
Vanderbilt University Medical Center and the global biopharmaceutical company AstraZeneca have joined forces to identify candidates for antibody-based treatments that could protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read MoreApr 9, 2020
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Race, hormones and diabetes risk
Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease. Read MoreApr 8, 2020
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Researchers developing potential coronavirus antibody therapies
Vanderbilt University Medical Center is teaming up with academic, governmental and corporate partners in an unprecedented, fast-tracked global effort to develop antibody-based treatments to protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read MoreApr 8, 2020
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Blocking stress-induced relapse
Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders. Read MoreApr 8, 2020
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Spasticity underdiagnosed
Spasticity — a consequence of stroke and other disorders of the central nervous system — may be underdiagnosed and undertreated in nursing home residents. Read MoreApr 8, 2020
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Study reveals an inherited origin of prostate cancer in families
Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease. Read MoreApr 8, 2020
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Cellular factor helps package flu genome
New insights on influenza genome packaging could guide strategies for interfering with the virus's life cycle and ability to cause infection. Read MoreApr 8, 2020
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VUMC team aids development of potential antiviral drug for COVID-19
Researchers at Vanderbilt University Medical Center are playing a key role in the development of a potential new antiviral drug to treat COVID-19. Read MoreApr 6, 2020
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Triple-negative breast cancer drug therapy shows promise
Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. Read MoreMar 12, 2020