Health And Medicine
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Therapeutic target for synovial sarcoma
Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read MoreNov 21, 2013
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Study finds limited resources for injured surgeons
Nearly half of orthopaedic surgeons sustain at least one injury during their career and, in many cases, the resources available to them are inadequate, according to a Vanderbilt study in The Journal of Bone & Joint Surgery. Read MoreNov 21, 2013
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Immunosuppressive drugs unlikely to raise fetal risk: study
Women with chronic autoimmune diseases who take immunosuppressive medications during their first trimester of pregnancy are not putting their babies at significantly increased risk of adverse outcomes, according to a Vanderbilt study released online by the journal Arthritis and Rheumatism. Read MoreNov 14, 2013
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Amish aid study of Parkinson genetics
Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles. Read MoreNov 11, 2013
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Defusing ‘C. diff’ infection
Clostridium difficile on the intestinal lining. (Wellcome Images) Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. Read MoreNov 8, 2013
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Neurotransmitter’s role in bone balance
Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling. Read MoreNov 7, 2013
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Breast SPORE lands NCI renewal
Vanderbilt-Ingram Cancer Center’s Breast Specialized Program of Research Excellence (SPORE) has been awarded a third round of funding from the National Cancer Institute (NCI). Read MoreNov 7, 2013
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Grant bolsters HIV pharmacy support program
The Vanderbilt Comprehensive Care Clinic has received a nearly $40,000 grant for 2013-2014 from the Baptist Healing Trust (BHT) for its Pharmacy Support Program, which provides free or low-cost medications to people with HIV/AIDS. Read MoreNov 7, 2013
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VU study sheds new light on DNA replication
David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes. Read MoreNov 7, 2013
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Knowing who their physician is boosts patient satisfaction
Knowing who your doctor is — and a couple of facts about that person — may go a long way toward improving patient satisfaction, according to a Vanderbilt study in the Journal of Orthopaedic Trauma. Read MoreOct 31, 2013
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Pioneers of Discovery: Investigator driven to divine cellular ecosystem’s rulebook
Ken Lau, Ph.D., a new assistant professor in Cell and Developmental Biology, is out to determine the rules that lead to cells converting from one type to another, for example, when a healthy cell becomes a cancer cell. Read MoreOct 31, 2013
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VU ‘crosslinks’ study sheds light on chemical toxicity
Vanderbilt researchers have characterized the chemical structures of a series of DNA-protein “crosslinks” that may lead to better ways to avoid the cancer-causing potential of environmental chemicals and prevent some drug toxicities. Read MoreOct 31, 2013
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Preserving antibiotic arsenal for TB
Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB. Read MoreOct 30, 2013
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Vanderbilt to study use of plasma on LifeFlight
Vanderbilt University Medical Center will participate in a national trial to see if outcomes for critically injured patients with uncontrolled bleeding can be improved by administering plasma to these patients while in flight to the hospital. Read MoreOct 29, 2013
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Tool predicts risk for developmental delays in early childhood
A non-invasive measure of electrical brain activity in preterm infants predicts cognitive and communication functioning during early childhood, according to a new Vanderbilt University study. Read MoreOct 28, 2013
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Targets of SIN drive cell division
Vanderbilt researchers have identified a key regulator of cell division. Read MoreOct 25, 2013
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Grad students help achieve key discovery
A multidisciplinary study conducted by the combined efforts of Vanderbilt University graduate students has led to the first evidence that abnormal messenger RNA export from the nucleus to the cytoplasm can cause human disease. Read MoreOct 24, 2013
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Glucose control study gives patients new path to health
The IDIOM study is designed to compare how a diet with moderate caloric restriction, alone or with long-acting insulin, affects areas of the brain’s dopamine system that are involved in food intake, reward and the sense of pleasure people get from eating. Read MoreOct 24, 2013
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Study sheds new light on type 2 diabetes development
Inactivation by oxidative stress of specific transcription factors essential for pancreatic islet beta cell function is a key event in the development of type 2 diabetes, Vanderbilt University researchers and their colleagues have found. Read MoreOct 24, 2013