Health And Medicine
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Study tracks new lung cancer drug target
Researchers at Vanderbilt University have identified a potential new drug target in subtypes of lung cancer that are difficult to treat. Read MoreApr 10, 2014
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Matrix remodeling and insulin resistance
The extracellular matrix that surrounds cells plays a role in the development of insulin resistance. Read MoreApr 10, 2014
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DBS for Parkinson’s trial moves to next level
A long-term Vanderbilt University Medical Center study of deep brain stimulation (DBS) in early-stage Parkinson’s disease has received approval from the Food and Drug Administration (FDA) to continue in a pivotal, phase III, large-scale safety and efficacy trial. Read MoreApr 3, 2014
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Protein’s role in spread of colon cancer studied
One of the most formidable weapons in a cancer’s arsenal is the ability to spread to other organs. Read MoreApr 3, 2014
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Grant aids search for Restless Legs Syndrome treatment
Vanderbilt University Medical Center has been selected as one of three sites to share a three-year, $1.3 million grant from the National Institutes of Health (NIH) to explore the potential therapeutic properties of manganese, a chemical element and biologically essential trace mineral, in treating Restless Legs Syndrome (RLS). Read MoreApr 3, 2014
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VU study tracks urinary incontinence therapy
More than 15 million women in the United States are impacted by stress urinary incontinence (SUI) at a cost of nearly $20 billion a year to treat. Read MoreApr 2, 2014
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Development and disease in the aorta
Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease. Read MoreApr 2, 2014
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E-records shed light on drug response
Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read MoreMar 31, 2014
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Mapping brain circuitry
Vanderbilt investigators have used two types of neuroimaging to establish a “map” of connections for a brain region important in anxiety and addiction. Read MoreMar 28, 2014
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Gut woes of preemies focus of microbiome effort
A multidisciplinary team of microbiome researchers at Vanderbilt University is shedding light on necrotizing enterocolitis (NEC), a disease of prematurity that kills hundreds of babies and costs the U.S. health care system an estimated $5 billion a year. Read MoreMar 27, 2014
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Grant bolsters patient-centered outcomes research
Patient-centered outcomes research is the focus of a $3.3 million, five-year, institutional K12 training grant awarded to Vanderbilt University Medical Center by the Agency for Healthcare Research and Quality (AHRQ). Read MoreMar 27, 2014
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Study links stem cell gene to prostate cancer susceptibility
A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found. Read MoreMar 27, 2014
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Flu boosts pneumococcal colonization
Influenza and parainfluenza infections – but not other respiratory viruses – increase the risk of acquiring pneumococcal bacteria, the most common cause of severe pneumonia. Read MoreMar 27, 2014
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Study team able to disrupt ‘building blocks’ of behavior
Researchers at Vanderbilt have been able to alter mouse behavior by silencing gene expression in interneurons, distinct populations of nerve cells that are the main regulators of brain circuits. Read MoreMar 20, 2014
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Small molecule protects kidney filter
A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier. Read MoreMar 19, 2014
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Delirium increases long-term disability
Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge. Read MoreMar 17, 2014
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Protein boosts retinal neuron survival
An ion channel protein called TRIPV1 helps retinal neurons survive the elevated eye pressure associated with glaucoma. Read MoreMar 14, 2014
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‘Missing link’ may spur new brain disorder drugs
Researchers at the Scripps Research Institute in San Diego and Vanderbilt University have discovered a “missing link” in the structure of a transmembrane receptor that could lead to new treatments for autism, schizophrenia, Parkinson’s disease and Alzheimer’s disease. Read MoreMar 13, 2014
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Viral illness may spur ‘standing up’ disorder
Circulating “autoantibodies” possibly triggered by a viral illness may contribute an abnormally rapid heart rate or tachycardia upon standing that affects 500,000 Americans, mostly young women, according to researchers at the University of Oklahoma and Vanderbilt University. Read MoreMar 13, 2014
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A new way to target cancer-driver Ras
Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way. Read MoreMar 13, 2014