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Author: Leigh MacMillan

New tool hooks heart failure drugs

Apr. 6, 2012—A new screening tool – using glowing fish embryos – could identify therapeutics for myocardial hypertrophy and heart failure.

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Plant compound quells inflammation

Apr. 6, 2012—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases.

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Obesity turns “good” cholesterol bad

Mar. 21, 2012—Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.

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iPOND method goes fishing for proteins

Mar. 19, 2012—A new tool will allow researchers to identify proteins involved in DNA replication and damage repair, processes that go awry in cancer.

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Immune system’s role in prematurity complication studied

Mar. 16, 2012—Disruptions in immune system regulation may play a role in a deadly complication in premature infants.

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Reversing lipid woes in cystic fibrosis

Mar. 3, 2012—Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA.

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‘Detangler’ binds, bends and cuts DNA

Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

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Studies pinpoint new anti-cancer drug target

Feb. 23, 2012—Vanderbilt researchers have discovered a new molecular participant in the Wnt signaling pathway, which plays important roles in cell growth, development and cancer.

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Stem cells take heart

Feb. 20, 2012—Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle.

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Memory intact in early psychosis

Feb. 16, 2012—Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities.

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Matchmaker for clinical studies

Feb. 8, 2012—ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies.

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Tool finds connections in genome data

Feb. 8, 2012—A new analytical tool points to genes that act together to increase disease risk.

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