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Author: Leigh MacMillan

Receptor’s role in nutrition brain circuitry

Jul. 3, 2012—New findings point to brain circuitry that communicates about the body’s nutritional status and regulates how nutrients are mobilized.

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Low oxygen could protect sick kidneys

Jun. 28, 2012—Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease.

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Roots of childhood brain tumors

Jun. 14, 2012—Cells in the back of the developing brain can give rise to brain tumors, suggesting they may be a target for treatment.

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DNA: From modification to mutation

Jun. 8, 2012—Understanding how an environmental hazard damages DNA may shed light on processes of tumor formation.

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Alzheimer’s protein structure suggests new treatment directions

May. 31, 2012—The molecular structure of a protein involved in Alzheimer’s disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the memory-robbing disease.

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Long live the therapeutic stem cells

May. 17, 2012—Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.

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Intestinal artillery launches anti-bacterial attack

May. 14, 2012—The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut.

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Probing epilepsy’s molecular sparks

May. 10, 2012—Understanding how mutations in neuronal receptors contribute to epilepsy could lead to improved therapies.

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Better blood pressure-reducing drugs?

Apr. 30, 2012—A newer version of an old class of blood pressure lowering drugs may offer advantages for obese patients with metabolic syndrome.

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Neuronal clues to cholesterol-defect disorder

Apr. 20, 2012—Antioxidants may be a beneficial treatment for an inherited genetic disorder.

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Pathways to delirium in the ICU

Apr. 17, 2012—Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.

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Researchers spot Achilles’ heel in respiratory virus

Apr. 13, 2012—A new viral protein structure could jump-start vaccine development for two leading causes of lower respiratory disease in children and elderly adults.

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