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Author: Leigh MacMillan

Neuronal subtypes in genetic disorder

Sep. 6, 2012—Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex.

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Targeting new pathways to ease pain

Aug. 30, 2012—The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics.

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Clues to retinal cell degeneration

Aug. 28, 2012—A reversible chemical modification of rhodopsin, a receptor for light, plays a role in the degeneration of retinal cells.

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VU, Lipscomb partner on dual degree program

Aug. 23, 2012—A new cooperative program between Vanderbilt University and Lipscomb University’s College of Pharmacy is focusing on the next generation of pharmaceutical researchers. By offering a pathway for students to earn both Pharm.D. and Ph.D. degrees, the program aims to boost the number of pharmacy-trained research scientists.

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Flu Tool guides patient decision-making

Aug. 14, 2012—Studies of Flu Tool, a computer application that guides health care decision-making, suggests that patients are willing to use these types of resources.

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New therapeutic target for cold, flu viruses identified

Aug. 9, 2012—Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells.

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Team creates new view of body’s infection response

Aug. 9, 2012—A new 3-D view of the body’s response to infection — and the ability to identify proteins involved in the response — could point to novel biomarkers and therapeutic agents for infectious diseases.

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Ancestry impacts smoking risk for lungs

Aug. 7, 2012—Smoking is more detrimental to lung function in individuals with high proportions of African ancestry.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Long antibodies better against HIV

Jul. 19, 2012—Understanding how antibodies with long “loops” form may be important for HIV vaccine development.

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VU study finds stress fuels breast cancer metastasis to bone

Jul. 18, 2012—Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

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Insights for neuroscience drug discovery

Jul. 17, 2012—When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

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