Paul Govern
-
Chemo for cancer lowers dementia risk
Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people. Read MoreMar 22, 2021
-
Artificial intelligence calculates suicide attempt risk at VUMC
A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center. Read MoreMar 15, 2021
-
Grant supports speedy sorting of health records by phenotype
Wei-Qi Wei, MD, PhD, assistant professor of Biomedical Informatics and scientific director of the Precision Phenotyping Core at the Center for Precision Medicine, has been awarded a four-year, $1.7 million grant from the National Institutes of Health to continue development of high-throughput software for quickly identifying traits of interest, or phenotypes, in electronic health records (EHRs). Read MoreFeb 11, 2021
-
Study will delve into EHR for signs of suicidality
Retrieval of clearer, more complete information from the EHR could go a long way toward improving predictive models of who will next be at risk of suicide, thereby improving care for patients with suicidal thoughts and behaviors. Read MoreFeb 11, 2021
-
Study finds recommended ICU sedatives equally safe, effective
Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia. Read MoreFeb 2, 2021
-
Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021
-
Building a cohort, the easy way
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions. Read MoreJan 7, 2021
-
Model students: improving clinical decision-making
Vanderbilt investigators have devised a system to alert health IT teams to deteriorating performance in clinical prediction models. Read MoreDec 10, 2020
-
Genes spell penicillin allergy risk
Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read MoreOct 1, 2020
-
Throwing weight around on the internet
What users mention in online weight loss forum tracks with how much weight they lose. Read MoreSep 21, 2020
-
VUMC to lay groundwork for Tennessee’s first federally funded Alzheimer’s Disease Research Center
Angela Jefferson, PhD, professor of Neurology and director of the Vanderbilt Memory and Alzheimer’s Center, has been awarded a $3.7 million, three-year grant from the National Institute on Aging (NIA) to support establishment of a prospective NIA-funded Alzheimer’s Disease Research Center (ADRC) at Vanderbilt University Medical Center. Read MoreSep 10, 2020
-
Study uses AI to sort patient messages by complexity
Taking an interest in electronic message threads between surgical patients and their health care teams, a research group at Vanderbilt University Medical Center has tested how well certain commonly used machine learning algorithms can classify such exchanges according to their clinical decision-making complexity. Read MoreAug 27, 2020
-
Land of plenty (of opioids)
Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read MoreAug 24, 2020
-
Cashew shell compound appears to mend damaged nerves
In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reported Aug. 17 in the Proceedings of the National Academy of Sciences. Read MoreAug 17, 2020
-
VUMC-led network to focus on polygenic risk for common diseases
With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes. Read MoreJul 1, 2020
-
All of Us program launches cloud-based research platform
On May 27, the All of Us Research Program launched the beta version of its cloud-based research platform, the Researcher Workbench. Read MoreJun 18, 2020
-
Yin receives early investigator MERIT Award from NCI
Zhijun Yin, PhD, assistant professor of Biomedical Informatics at Vanderbilt University Medical Center, has received the National Cancer Institute’s Method to Extend Research in Time Award (or MERIT Award) for Early Stage Investigators. Read MoreMay 14, 2020
-
Damage, disruption, delirium
New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients. Read MoreApr 20, 2020
-
Spasticity underdiagnosed
Spasticity — a consequence of stroke and other disorders of the central nervous system — may be underdiagnosed and undertreated in nursing home residents. Read MoreApr 8, 2020
-
Grant bolsters research on subjective cognitive decline
Katherine Gifford, PsyD, MS, assistant professor of Neurology, has been awarded a five-year, $4.3 million research grant from the National Institute on Aging to study what subjective cognitive decline can reveal about underlying pathology. Read MoreFeb 27, 2020