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Vanderbilt study links gene expression, disease association data

by Jul. 27, 2018, 8:46 AM

An international team of researchers has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases. In a study led by Eric Gamazon, PhD, research instructor in Medicine at Vanderbilt, and Ayellet Segrè, PhD, of Harvard University, the team developed computational approaches to integrate the two types of data and link disease-associated genetic variants to gene expression in a broad collection of human tissues. They also identified hundreds of additional variants in the genome that predispose people to disease.

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