The Commodores extended their year well beyond the regular season and came within one game of moving on to the College World Series. The team finished with a 46–20 overall record. After a 40–15 regular season finish, Vanderbilt exited the SEC Tournament with losses to LSU and Florida, but won the NCAA Regional Tournament at Louisville, advancing from the loser’s bracket to take the title with a 4–1 record. The next stop was Tallahassee and the NCAA Tournament Super Regional against Florida State. Vanderbilt won the first game but dropped the next two, ending the 2010 season.