Zhongming Zhao

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action. Read More

Prospecting for genes that might be implicated in cancer, a Vanderbilt University Medical Center research team has struck pay dirt. Read More

Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response. Read More

When something attacks you, you want to attack it back. That’s how Lillian “Tooty” Bradford views her late husband James “Jimmy” Bradford Jr.’s decision to make an initial gift to fund melanoma research at Vanderbilt-Ingram Cancer Center (VICC). Read More

Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder. Read More

Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies. Read More

The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis. Read More

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read More

Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay. Read More

Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines. Read More

MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read More

An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to a specific drug therapy, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation. Read More

A new catalog of human genetic data may help researchers uncover the genetic roots of disease and enable the ultimate realization of personalized medicine. Read More

A new analytical tool points to genes that act together to increase disease risk. Read More