Psychosis

  • Istock image of neurons in the brain

    White matter and psychosis

    The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read More

    Jan 27, 2022

  • thalamus

    Pinpointing brain changes in psychosis

    Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

    Oct 1, 2020

  • illustration of head dissolving into pixels

    Relational memory in early psychosis

    Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis. Read More

    Sep 10, 2019

  • Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

    Working memory in psychotic disorders

    Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders. Read More

    Jul 11, 2019

  • sad or anxious young white man sitting on front porch of apartment building with his hands clasped

    Early detection of schizophrenia

    Inhibited temperament—a tendency to respond to novelty with wariness, fear or caution—may be a risk factor for schizophrenia that could be targeted for preventative interventions. Read More

    Jun 24, 2019

  • Vanderbilt University

    Shared genetics may shape treatment options for certain brain disorders

    Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting. Read More

    Jun 14, 2018

  • Vanderbilt University

    Brain circuitry in psychosis

    Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More

    Aug 21, 2015

  • Vanderbilt University

    Insights for neuroscience drug discovery

    When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects. Read More

    Jul 17, 2012

  • Brain image

    Memory intact in early psychosis

    Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read More

    Feb 16, 2012

  • Vanderbilt University

    Managing psychosis topic of Feb. 21 lecture

    (iStockphoto) Vanderbilt University Medical Center, the Department of Nursing Education and Professional Development and the Center for Quality Aging present a Geriatrics and Gerontology Interest Group lunchtime lecture on psychosis, agitation and their management with psychotropic medications. Harry Gwirtsman, associate professor of psychiatry and an expert in… Read More

    Feb 15, 2012

  • Vanderbilt University

    Information flow reduced in psychosis

    Bipolar depression and schizophrenia share patterns of changes in neurons that regulate information flow, new research shows. Read More

    Oct 21, 2011