PLoS Pathogens
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Temperature, newts, and a skin-eating fungus
The emergence of pathogenic skin fungi that cause the disease chytridiomycosis is contributing to the global loss of amphibian populations. Read MoreMar 8, 2021
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Key factors in HIV-1 replication
HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication. Read MoreFeb 8, 2021
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Study’s findings may help eventually close the door on COVID-19
Researchers at Vanderbilt University Medical Center and the University of Texas Medical Branch (UTMB) at Galveston have discovered what may be the Achilles’ heel of the coronavirus, a finding that may help close the door on COVID-19 and possibly head off future pandemics. Read MoreJan 28, 2021
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Antibodies eye Pacific Island “fever”
Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read MoreMay 14, 2020
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018
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Bacterial secretion machinery: 3-D view
New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells. Read MoreDec 11, 2014
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Host sequesters zinc to control stomach bug
Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk. Read MoreNov 21, 2014
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Anthrax bacteria’s signaling systems
Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host. Read MoreApr 15, 2014
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‘Proofreader’ key to coronavirus growth
A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses. Read MoreSep 12, 2013
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Zinc: a new antibiotic target?
It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read MoreJan 17, 2013