Peter Hedera

Melissa Darnall could easily look around her family reunions and pick out who had Huntington’s disease (HD). The genetic disorder had affected four of her five aunts and uncles and her father, and the balance problems and shakiness typical of HD were readily apparent in those siblings. Read More

Peter Hedera, M.D. Hereditary spastic paraplegia (HSP), a group of progressive neurodegenerative disorders that impairs the ability to walk, can be caused by mutations in more than 40 different genes. Despite this genetic heterogeneity, the pathologic features – degeneration of long axons in the spinal cord – are relatively uniform,… Read More