Pain
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Loss of ‘Jedi’ alters neuron activity
This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain. Read MoreMar 10, 2020
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Gender, pain and dementia
Understanding sex differences in pain perception could lead to more targeted and effective pain assessment and management strategies in older adults with Alzheimer’s disease. Read MoreOct 16, 2017
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Pain and Alzheimer’s disease
Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read MoreSep 5, 2017
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New pain medicine from a fungus?
Collybolide – a natural product isolated from a mushroom – is a promising candidate for the development of non-addictive pain medicines. Read MoreMay 13, 2016
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The yin and yang of COX-2
New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read MoreOct 2, 2015
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How the cell makes morphine
Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine. Read MoreAug 25, 2015
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New apps increase efficiency and safety for anesthesiologists
Vanderbilt’s Department of Anesthesiology and the American Society of Regional Anesthesia and Pain Medicine (ASRA) have teamed to provide anesthesiologists with new applications to improve workflow and safety practices. Read MoreJun 25, 2015
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A pain in the … genes
Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read MoreJan 10, 2014
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Toxin provides endometriosis clues
Environmental toxins may contribute to endometriosis-related infertility by disrupting endometrial response to progesterone. Read MoreNov 2, 2012
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Targeting new pathways to ease pain
The spinal cord’s neuropeptide Y signaling pathway may be a good target for new pain therapeutics. Read MoreAug 30, 2012