P450
-
Codeine metabolizer status in clinical practice
Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine. Read MoreApr 5, 2021
-
Steroid binding to metabolic enzyme
Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer. Read MoreJun 12, 2019
-
Altered metabolism and disease
Vanderbilt researchers report a structure of a human metabolic enzyme bound to its substrate 17alpha-hydroxyprogesterone. Read MoreJul 25, 2017
-
Antacids: risky for premature babies
Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants. Read MoreJun 12, 2013
-
An orphan enzyme’s purpose
“Orphan” enzyme may play role in cancer growth, new research suggests. Read MoreOct 4, 2012