NIH
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Brain tumor TIP reveals new target
The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development. Read MoreFeb 4, 2013
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Cell source of heart’s blood vessels
An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read MoreFeb 1, 2013
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Do-it-yourself repair in the kidney
The kidney can mediate its own repair through proliferation of resident immune system cells. Read MoreJan 31, 2013
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New tool for mining bacterial genome for novel drugs
Vanderbilt biochemists have discovered that the process bacteria undergo when they become drug resistant can act as a powerful tool for drug discovery. Read MoreJan 25, 2013
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VKC’s Science Day explores promise of research
Recent advances in genetics and understanding how the brain works raise the possibility that intellectual developmental disabilities are treatable and some actually may be reversible. Read MoreJan 24, 2013
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New view of DNA processing ‘hub’
Structural studies reveal a new framework for understanding a central player in DNA processing. Read MoreJan 23, 2013
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HDL cholesterol impaired in kidney disease
HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read MoreJan 21, 2013
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Seeing light receptor’s interactions
Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read MoreJan 18, 2013
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Study helps define pancreatic cancer’s cellular origins
Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read MoreJan 17, 2013
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Zinc: a new antibiotic target?
It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read MoreJan 17, 2013
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Preventing hardened heart valves
Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read MoreDec 26, 2012
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A drug combo for ovarian cancer
Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read MoreDec 24, 2012
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Low prenatal alcohol’s brain impact
Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds. Read MoreDec 21, 2012
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Cancer markers from archived tissue
Archived tissue samples are yielding new disease biomarkers. Read MoreDec 20, 2012
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Genes, nutrients interact to shape traits
A new study identifies interactions between genes and nutrients that may participate in determining levels of cholesterol and triglycerides. Read MoreDec 12, 2012
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Genetic clues to lung scarring
A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases. Read MoreDec 10, 2012
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Polarity protein suppresses tumor growth, invasion
The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read MoreNov 29, 2012
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Carcinogenic chemicals cramp DNA
Researchers have determined how a DNA lesion caused by exposure to chemicals may spark cancer formation. Read MoreNov 21, 2012
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Bird’s eye view of gut development
A new map of the developing gut of quail offers valuable tool for studying intestinal diseases. Read MoreNov 19, 2012
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Green tea for failing hearts?
The main antioxidant compound in green tea increases contractile force in isolated heart cells, suggesting it may be useful in heart failure. Read MoreNov 16, 2012