NIH
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New lead for ovarian cancer treatment
Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer. Read MoreDec 10, 2015
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Microtubules act as cellular ‘rheostat’ to control insulin secretion
Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read MoreDec 3, 2015
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Kenworthy to chair NIH biochemistry study section
Anne Kenworthy, Ph.D., professor of Molecular Physiology and Biophysics, has been named to a two-year term as chair of the Biochemistry and Biophysics of Membranes Study Section in the Center for Scientific Review of the National Institutes of Health (NIH). Read MoreDec 3, 2015
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Caucus explores crucial role of NIH research funding
James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, and Anthony Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), recently participated in a U.S. Senate National Institutes of Health (NIH) caucus briefing held in Washington, D.C., by Senate NIH caucus co-chairs Sens. Lindsey Graham (R-SC) and Dick Durbin (D-IL). Read MoreDec 3, 2015
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Study links opioids, infection risk for patients with rheumatoid arthritis
Use of opioid analgesics is associated with an increased risk of hospitalization for serious infections among patients with rheumatoid arthritis, according to a Vanderbilt study published in Arthritis & Rheumatology. Read MoreNov 19, 2015
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Fighting type 2 diabetes with FGF1
The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes. Read MoreNov 18, 2015
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Children, heart disease, and IQ
Treatment for congenital heart disease during infancy may result in cognitive and attentional deficits during adolescence and young adulthood, Vanderbilt researchers have found. Read MoreNov 16, 2015
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Immune system a must for kidney repair
A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells. Read MoreNov 12, 2015
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Study helps clarify components of DNA ‘copy machine’
Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read MoreNov 12, 2015
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MLK student advances in Siemens competition with Vanderbilt collaboration
Another participant in the School for Science and Math at Vanderbilt has advanced in the Siemens Competition in Math, Science and Technology. Read MoreNov 9, 2015
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Study further links immune response, serotonin signaling
Vanderbilt University scientists are a step closer to understanding how inflammation in the body can affect mood and behavior. Read MoreNov 5, 2015
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Detect and defend against pathogens
Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read MoreNov 4, 2015
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VUMC receives NIH grant to develop artificial kidney
The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center (VUMC) and the University of California at San Francisco (UCSF) to develop an implantable artificial kidney. Read MoreNov 3, 2015
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Prenatal folic acid and asthma
The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study. Read MoreOct 30, 2015
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Inflammation, obesity and diabetes
Vanderbilt study adds to the mounting role for inflammatory signaling in obesity. Read MoreOct 29, 2015
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Compound developed at VUMC may delay Huntington’s disease
A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder. Read MoreOct 29, 2015
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Healing without scarring
Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer. Read MoreOct 16, 2015
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Risk of death in the ICU
The irregular heart rhythm atrial fibrillation increases the risk of death in patients in the intensive care unit. Read MoreOct 15, 2015
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VUSN Alzheimer’s study to explore perception of pain
Vanderbilt University School of Nursing (VUSN) has been awarded a four-year $660,633 grant from the National Institute of Health’s National Institute on Aging to study how psychophysical responses to acute experimental thermal pain differ between older adults with and without Alzheimer’s Disease (AD). Read MoreOct 15, 2015
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Potential target for lung cancer therapy
The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read MoreOct 5, 2015