Kidney Failure
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VUMC scientists discover key step to kidney fibrosis
Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure. Read MoreNov 21, 2023
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Gene variants increase risk of kidney failure in Black veterans with COVID-19: study
Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read MoreFeb 10, 2022
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VUMC study raises hope for improving treatment of kidney disease
Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read MoreFeb 2, 2022
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Implant one day may replace dialysis
Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device. Read MoreMay 18, 2020
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Immune system a must for kidney repair
A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells. Read MoreNov 12, 2015
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Research effort seeks to improve home care for kidney failure patients
Vanderbilt nephrologist, Thomas Golper, M.D., professor of Medicine in Nephrology and Hypertension, is leading an effort to form a research consortium with a goal of improving care for kidney failure patients who receive a form of home dialysis. Read MoreJun 27, 2013
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‘Longevity’ gene aids kidney survival
A gene associated with cell survival and longevity may protect the kidney from acute injury. Read MoreApr 17, 2013
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Meds’ benefits differ in dialysis patients
About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to… Read MoreJan 5, 2012