Journal Of Immunology
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Tracking lung macrophages
A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury. Read MoreMay 4, 2023
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Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read MoreJan 27, 2022
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A new regulator of B cell development
New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells. Read MoreOct 8, 2019
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Novel infection fighter
A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections. Read MoreJun 13, 2018
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Disease-fighting antibody production
New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read MoreApr 20, 2018
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Predicting the infection response
Vanderbilt investigators are probing the response to a bacterial toxin as a clinical assessment of immune function. Read MoreApr 19, 2017
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Pathology of septic shock
The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection. Read MoreFeb 8, 2017
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Restore T cells to fight leukemia
Modulation of T cell metabolism thus may represent a new therapeutic avenue for leukemia patients. Read MoreSep 14, 2016
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“Silent” B cells trigger autoimmunity
Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes. Read MoreApr 3, 2013
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Target for inflammatory bowel disease
The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read MoreMar 1, 2013
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Low oxygen could protect sick kidneys
Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease. Read MoreJun 28, 2012