Iron
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Novel C. diff structures are required for infection, offer new therapeutic targets
Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs. Read MoreNov 15, 2023
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Study discovers role for gut bacteria in host-pathogen competition for nutrients
Vanderbilt research shows that commensal gut microbes impact the host-pathogen competition for iron and have implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients. Read MoreOct 27, 2023
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Imaging host-pathogen battle for metal
An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies. Read MoreOct 31, 2019
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Iron-sulfur “intersection”
Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia. Read MoreMar 8, 2018
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Lighting up iron levels
A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read MoreJan 11, 2018
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Linking oxygen, iron and red blood cells
The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read MoreFeb 6, 2013