HDL
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Study suggests new mechanism for lipid transporter
A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought. Read MoreSep 15, 2022
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Potential protection from atherosclerosis
Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read MoreAug 19, 2021
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A new contributor to atherosclerosis
Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read MoreJan 27, 2020
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HDL-cholesterol and breast cancer risk
Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy. Read MoreJan 23, 2020
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Scavengers “protect” HDL
Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read MoreJun 29, 2018
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Understanding HDL structure
Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read MoreMay 3, 2018
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HDL and kidney injury after surgery
Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read MoreJan 17, 2018
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Kidney disease impacts HDL function
Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read MoreFeb 11, 2015
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Major grant spurs deeper look into ‘good cholesterol’
In some cases, HDL, the "good cholesterol," may not function properly and may actually accelerate atherosclerosis. Read MoreAug 21, 2014
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HDL cholesterol impaired in kidney disease
HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read MoreJan 21, 2013
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Gene’s impact on ‘good’ cholesterol could affect heart disease risk
A genetic variant may help keep an individual’s “good” cholesterol in check. Read MoreJul 12, 2012
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Obesity turns “good” cholesterol bad
Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol. Read MoreMar 21, 2012