Division Of Nephrology And Hypertension
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Blood mutations increase risk for acute kidney injury: study
A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide. Read MoreMar 7, 2024
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VUMC study finds molecular switch key to repair of kidney damage
Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair. Read MoreFeb 7, 2024
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VUMC researchers upend dogma about vasopressin production
Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read MoreJan 5, 2023
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Study supports removing race from estimate of kidney function
An in-depth analysis by Vanderbilt investigators of published research studies supports removing race from the calculation of estimated glomerular filtration rate (eGFR) — an assessment of kidney function. Read MoreNov 17, 2022
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Study sheds light on the dark side of obesity
Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity. Read MoreMay 12, 2022
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Gene variants increase risk of kidney failure in Black veterans with COVID-19: study
Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read MoreFeb 10, 2022
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The role of integrins in kidney “integrity”
Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered. Read MoreJan 13, 2022
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Gene expression in diabetic nephropathy
Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read MoreAug 5, 2021
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Clue to diabetic kidney disease
Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read MoreOct 5, 2020
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Protecting the injured kidney
Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it. Read MoreJun 4, 2020
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Implant one day may replace dialysis
Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device. Read MoreMay 18, 2020
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Barbershops targeted to improve health of black men
Black men with high blood pressure could benefit from a research study beginning this month to check their vitals while they are getting a haircut at a barbershop. Read MoreFeb 18, 2020
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Ikizler to succeed Harris as Nephrology and Hypertension director
T. Alp Ikizler, MD, an internationally known expert on the nutritional and metabolic aspects of kidney disease, will succeed Raymond Harris, MD, as director of the Department of Medicine’s Division of Nephrology and Hypertension in the Vanderbilt University School of Medicine effective July 1. Read MoreJun 28, 2018
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Research explores barriers to kidney disease screening
New research by Vanderbilt nephrologists highlights potential barriers that may prevent black Americans from being screened for kidney disease. Read MoreMar 15, 2018
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Major grant to enhance kidney disease research
Vanderbilt’s Division of Nephrology and Hypertension has received a five-year, $5 million federal grant to provide core research services in the fight against kidney disease. Read MoreSep 28, 2017
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Vanderbilt, Bayer collaborate to develop new therapies against kidney diseases
Vanderbilt University Medical Center (VUMC) and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development. Read MoreSep 11, 2017
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End-stage kidney disease study seeks to delay dialysis
Vanderbilt University Medical Center (VUMC) is studying the safety of a possible treatment for diabetic kidney disease that would delay or prevent the need for kidney replacement such as dialysis. Read MoreAug 31, 2017
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EETs contribute to insulin sensitivity
Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read MoreMay 11, 2017
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Building the basement membrane
Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues. Read MoreNov 21, 2016
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VUMC mourns loss of Nephrology’s Schulman
Gerald Schulman, M.D., professor of Medicine, died Aug. 26. He was 65. Read MoreAug 30, 2016