Department Of Biochemistry

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity. Read More

Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing. Read More

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme. Read More

Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer. Read More

David Cortez and colleagues have discovered a new DNA repair mechanism. Read More

Craig Lindsley, co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been named a fellow of the National Academy of Inventors. Read More

New Vanderbilt University biochemistry professor Houra Merrikh is working to defeat drug-resistant superbugs by blocking a molecule they need to mutate rapidly. Read More

Katherine Rothamel, a Ph.D. student in the Department of Biochemistry at Vanderbilt University School of Medicine, has been selected as the 2017 Vanderbilt Prize Student Scholar. Read More

Biochemistry professor Richard Caprioli, director of the Mass Spectrometry Research Center, and Jeff Spraggins, research assistant professor of biochemistry, and their team will build a platform to molecularly characterize cells. Read More

The Department of Biochemistry will present the inaugural Richard Armstrong Mentoring Award to Dr. Neil Osheroff, the John Coniglio Chair and professor of biochemistry, from noon to 1 p.m. Friday, Sept. 14, in Light Hall, Room 214. Read More

James Galligan and Lawrence Marnett have discovered a new histone modification that can affect gene expression. Read More

A $1 million gift has established a new faculty chair within the School of Medicine’s Basic Sciences that is named in honor of the late biochemist Richard Armstrong. Read More

David Cortez and colleagues have found that a protein called RADX helps modulate a protein called RAD51 in order to make sure exactly the correct amount of DNA repair occurs. Read More

The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system. Read More

Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read More

It’s not often that a keynote speaker will ask his audience to close their eyes and tune him out, but that’s what Aviad “Adi” Haramati, PhD, did when delivering the 2018 John E. Chapman Lecture. Read More

Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment. Read More

Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read More

An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research. Read More

New agreement will pursue therapies targeting MCL1 (myeloid cell leukemia 1), which is highly prevalent in many difficult-to-treat cancers. Read More