Collagen
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Potential new cancer target
Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis. Read MoreJun 4, 2020
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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism
An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read MoreJan 13, 2020
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New window on fibrosis
A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases. Read MoreAug 8, 2019
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Building the basement membrane
Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues. Read MoreNov 21, 2016
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How to build a basement
Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read MoreSep 9, 2015
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Molecular ‘chat’ holds kidney fibrosis clues
A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process. Read MoreJul 10, 2014