Brain And Behavior Research Foundation

Vanderbilt researchers push research on ketamine’s role as a rapid antidepressant another step forward. This work opens avenues for new therapeutics for half of people for whom today’s antidepressants don’t work. Read More

Discovery shows that dopamine is not a reward molecule at all, calling for revision of textbook facts regarding the hormone’s role in the brain. Est. reading time: 3.5 mins. Read More

Even in the absence of brain activity, nerve cells can turn on gene expression that is important for antidepressant effects. This novel finding from Lisa Monteggia gives researchers a more fundamental understanding of the brain’s mechanistic function for better therapeutics. Est. reading time: 2.5 mins. Read More

Exercise and movement may be a prescription to mitigate drug and alcohol seeking behavior due to its influence on the brain. Est. reading time: 3 mins. Read More

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read More