Biological Psychiatry
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Histamine circuits in brain reward center
Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction. Read MoreOct 29, 2020
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Brain aging occurs at accelerated rate in patients with psychosis
Normal brain aging patterns in patients with a psychotic disorder occur at an accelerated rate, impacting the patient’s cognitive functioning and suggesting treatment intervention in the early psychosis period may improve long-term outcomes. Read MoreMar 7, 2019
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Brain connections in schizophrenia
Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read MoreMar 9, 2018
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Study helps map signaling system in brain linked to ASD
Researchers at Vanderbilt University have worked out part of the “wiring diagram” of a signaling system in the brain that has been linked to autism spectrum disorder (ASD). Read MoreFeb 8, 2018
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Regulating anxiety in the brain
Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both. Read MoreApr 28, 2017
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Probing drug abuse circuitry
Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders. Read MoreNov 4, 2016
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Brain circuitry in psychosis
Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read MoreAug 21, 2015
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Skin biopsy to diagnose depression?
It may be possible to use skin cells as biomarkers to diagnose and manage depression. Read MoreAug 29, 2014
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Antioxidants promising for rare disorder
The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development. Read MoreFeb 6, 2014
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Memory intact in early psychosis
Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read MoreFeb 16, 2012